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Asking ChatGPT a health-related question? Better keep it simple

<p>It’s tempting to <a href="https://cosmosmagazine.com/news/chatgpt-and-dr-google/">turn to search engines</a> to seek out health information, but with the rise of large language models, like ChatGPT, people are becoming more and more likely to depend on AI for answers too.</p> <div class="copy"> <p>Concerningly, an Australian study has now found that the more evidence given to <a href="https://cosmosmagazine.com/technology/chatgpt-an-intimate-companion/">ChatGPT</a> when asked a health-related question, the less reliable it becomes.</p> <p>Large language models (LLM) and artificial intelligence use in health care is still developing, creating a  a critical gap when providing incorrect answers can have serious consequences for people’s health.</p> <p>To address this, scientists from Australia’s national science agency, CSIRO, and the University of Queensland (UQ) explored a hypothetical scenario: an average person asking ChatGPT if ‘X’ treatment has a positive effect on condition ‘Y’.</p> <p>They presented ChatGPT with 100 questions sourced from the <a href="https://trec-health-misinfo.github.io/" target="_blank" rel="noopener">TREC Health Misinformation track</a> – ranging from ‘Can zinc help treat the common cold?’ to ‘Will drinking vinegar dissolve a stuck fish bone?’</p> <p>Because queries to search engines are typically shorter, while prompts to a LLM can be far longer, they posed the questions in 2 different formats: the first as a simple question and the second as a question biased with supporting or contrary evidence.</p> <p>By comparing ChatGPT’s response to the known correct response based on existing medical knowledge, they found that ChatGPT was 80% accurate at giving accurate answers in a question-only format. However, when given an evidence-biased prompt, this accuracy reduced to 63%, which was reduced again to 28% when an “unsure” answer was allowed. </p> <p>“We’re not sure why this happens,” says CSIRO Principal Research Scientist and Associate Professor at UQ, Dr Bevan Koopman, who is co-author of the paper.</p> <p>“But given this occurs whether the evidence given is correct or not, perhaps the evidence adds too much noise, thus lowering accuracy.”</p> <p>Study co-author Guido Zuccon, Director of AI for the Queensland Digital Health Centre at UQ says that major search engines are now integrating LLMs and search technologies in a process called Retrieval Augmented Generation.</p> <p>“We demonstrate that the interaction between the LLM and the search component is still poorly understood, resulting in the generation of inaccurate health information,” says Zuccon.</p> <p>Given the widespread popularity of using LLMs online for answers on people’s health, Koopman adds, we need continued research to inform the public about risks and to help them optimise the accuracy of their answers.</p> <p>“While LLMs have the potential to greatly improve the way people access information, we need more research to understand where they are effective and where they are not.”</p> <p><em>Image credits: Getty Images</em></p> <div> <p align="center"> </p> </div> <p><em><img id="cosmos-post-tracker" style="opacity: 0; height: 1px!important; width: 1px!important; border: 0!important; position: absolute!important; z-index: -1!important;" src="https://syndication.cosmosmagazine.com/?id=301406&amp;title=Asking+ChatGPT+a+health-related+question%3F+Better+keep+it+simple" width="1" height="1" loading="lazy" aria-label="Syndication Tracker" data-spai-target="src" data-spai-orig="" data-spai-exclude="nocdn" /></em><em><a href="https://cosmosmagazine.com/technology/ai/asking-chatgpt-a-health-related-question-better-keep-it-simple/">This article</a> was originally published on <a href="https://cosmosmagazine.com">Cosmos Magazine</a> and was written by <a href="https://cosmosmagazine.com/contributor/imma-perfetto/">Imma Perfetto</a>. </em></div>

Caring

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Leap of imagination: how February 29 reminds us of our mysterious relationship with time and space

<p><em><a href="https://theconversation.com/profiles/emily-ohara-874665">Emily O'Hara</a>, <a href="https://theconversation.com/institutions/auckland-university-of-technology-1137">Auckland University of Technology</a></em></p> <p>If you find it intriguing that February 28 will be followed this week by February 29, rather than March 1 as it usually is, spare a thought for those alive in 1582. Back then, Thursday October 4 was followed by Friday October 15.</p> <p>Ten whole days were snatched from the present when Pope Gregory XIII issued a papal bull to “restore” the calendar from discrepancies that had crept into the Julian calendar, introduced by Julius Caesar in 45 BCE.</p> <p>The new Gregorian calendar returned the northern hemisphere’s vernal equinox to its “proper” place, around March 21. (The equinox is when the Earth’s axis is tilted neither toward nor away from the sun, and is used to determine the date of Easter.)</p> <p>The Julian calendar had observed a leap year every four years, but this meant time had drifted out of alignment with the dates of celestial events and astronomical seasons.</p> <p>In the Gregorian calendar, leap days were added only to years that were a multiple of four – like 2024 – with an exception for years that were evenly divisible by 100, but not 400 – like 1700.</p> <p>Simply put, leap days exist because it doesn’t take a neat 365 days for Earth to orbit the Sun. It takes 365.2422 days. Tracking the movement of celestial objects through space in an orderly pattern doesn’t quite work, which is why we have February – time’s great mop.</p> <h2>Time and space</h2> <p>This is just part of the history of how February – the shortest month, and originally the last month in the Roman calendar – came to have the job of absorbing those inconsistencies in the temporal calculations of the world’s most commonly used calendar.</p> <p>There is plenty of <a href="https://theconversation.com/leap-day-fixing-the-faults-in-our-stars-54032">science</a>, <a href="https://theconversation.com/explainer-the-science-behind-leap-years-and-how-they-work-54788">maths</a> and <a href="https://theconversation.com/how-a-seasonal-snarl-up-in-the-mid-1500s-gave-us-our-strange-rules-for-leap-years-132659">astrophysics</a> explaining the relationship between time and the planet we live on. But I like to think leap years and days offer something even more interesting to consider: why do we have calendars anyway?</p> <p>And what have they got to do with how we understand the wonder and strangeness of our existence in the universe? Because calendars tell a story, not just about time, but also about space.</p> <p>Our reckoning of time on Earth is through our spatial relationship to the Sun, Moon and stars. Time, and its place in our lives, sits somewhere between the scientific, the celestial and the spiritual.</p> <p>It is <a href="https://shop.whitechapelgallery.org/products/time">notoriously slippery, subjective and experiential</a>. It is also marked, tracked and determined in myriad ways across different cultures, from tropical to solar to <a href="https://www.stuff.co.nz/pou-tiaki/300062097/matariki-and-the-maramataka-the-mori-lunar-calendar">lunar</a> calendars.</p> <p>It is the Sun that measures a day and gives us our first reference point for understanding time. But it is the <a href="https://librarysearch.aut.ac.nz/vufind/Record/1145999?sid=25214690">Moon</a>, as a major celestial body, that extends our perception of time. By stretching a span of one day into something longer, it offers us a chance for philosophical reflection.</p> <p>The Sun (or its effect at least) is either present or not present. The Moon, however, goes through phases of transformation. It appears and disappears, changing shape and hinting that one night is not exactly like the one before or after.</p> <p>The Moon also has a distinct rhythm that can be tracked and understood as a pattern, giving us another sense of duration. Time is just that – overlapping durations: instants, seconds, minutes, hours, days, weeks, months, years, decades, lifetimes, centuries, ages.</p> <h2>The elusive Moon</h2> <p>It is almost impossible to imagine how time might feel in the absence of all the tools and gadgets we use to track, control and corral it. But it’s also hard to know what we might do in the absence of time as a unit of productivity – a measurable, dispensable resource.</p> <p>The closest we might come is simply to imagine what life might feel like in the absence of the Moon. Each day would rise and fall, in a rhythm of its own, but without visible reference to anything else. Just endless shifts from light to dark.</p> <p>Nights would be almost completely dark without the light of the Moon. Only stars at a much further distance would puncture the inky sky. The world around us would change – trees would grow, mammals would age and die, land masses would shift and change – but all would happen in an endless cycle of sunrise to sunset.</p> <p>The light from the Sun takes <a href="https://www.skyatnightmagazine.com/space-science/how-take-light-from-sun-reach-earth">eight minutes</a> to reach Earth, so the sunlight we see is always eight minutes in the past.</p> <p>I remember sitting outside when I first learned this, and wondering what the temporal delay might be between me and other objects: a plum tree, trees at the end of the street, hills in the distance, light on the horizon when looking out over the ocean, stars in the night sky.</p> <p>Moonlight, for reference, takes about <a href="https://www.pbs.org/seeinginthedark/astronomy-topics/light-as-a-cosmic-time-machine.html">1.3 seconds</a> to get to Earth. Light always travels at the same speed, it is entirely constant. The differing duration between how long it takes for sunlight or moonlight to reach the Earth is determined by the space in between.</p> <p>Time on the other hand, is anything but constant. There are countless ways we characterise it. The mere fact we have so many calendars and ways of describing perceptual time hints at our inability to pin it down.</p> <p>Calendars give us the impression we can, and have, made time predictable and understandable. Leap years, days and seconds serve as a periodic reminder that we haven’t.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/224503/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><a href="https://theconversation.com/profiles/emily-ohara-874665"><em>Emily O'Hara</em></a><em>, Senior Lecturer, Spatial Design + Temporary Practices, <a href="https://theconversation.com/institutions/auckland-university-of-technology-1137">Auckland University of Technology</a></em></p> <p><em>Image credits: Shutterstock </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/leap-of-imagination-how-february-29-reminds-us-of-our-mysterious-relationship-with-time-and-space-224503">original article</a>.</em></p>

Technology

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Why it’s a bad idea to mix alcohol with some medications

<p><em><a href="https://theconversation.com/profiles/nial-wheate-96839">Nial Wheate</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/jasmine-lee-1507733">Jasmine Lee</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/kellie-charles-1309061">Kellie Charles</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>, and <a href="https://theconversation.com/profiles/tina-hinton-329706">Tina Hinton</a>, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a></em></p> <p>Anyone who has drunk alcohol will be familiar with how easily it can lower your social inhibitions and let you do things you wouldn’t normally do.</p> <p>But you may not be aware that mixing certain medicines with alcohol can increase the effects and put you at risk.</p> <p>When you mix alcohol with medicines, whether prescription or over-the-counter, the medicines can increase the effects of the alcohol or the alcohol can increase the side-effects of the drug. Sometimes it can also result in all new side-effects.</p> <h2>How alcohol and medicines interact</h2> <p>The chemicals in your brain maintain a delicate balance between excitation and inhibition. Too much excitation can lead to <a href="https://www.medicalnewstoday.com/articles/324330">convulsions</a>. Too much inhibition and you will experience effects like sedation and depression.</p> <p><iframe id="JCh01" class="tc-infographic-datawrapper" style="border: none;" src="https://datawrapper.dwcdn.net/JCh01/1/" width="100%" height="400px" frameborder="0"></iframe></p> <p>Alcohol works by increasing the amount of inhibition in the brain. You might recognise this as a sense of relaxation and a lowering of social inhibitions when you’ve had a couple of alcoholic drinks.</p> <p>With even more alcohol, you will notice you can’t coordinate your muscles as well, you might slur your speech, become dizzy, forget things that have happened, and even fall asleep.</p> <p>Medications can interact with alcohol to <a href="https://awspntest.apa.org/record/2022-33281-033">produce different or increased effects</a>. Alcohol can interfere with the way a medicine works in the body, or it can interfere with the way a medicine is absorbed from the stomach. If your medicine has similar side-effects as being drunk, those <a href="https://www.drugs.com/article/medications-and-alcohol.html#:%7E:text=Additive%20effects%20of%20alcohol%20and,of%20drug%20in%20the%20bloodstream.">effects can be compounded</a>.</p> <p>Not all the side-effects need to be alcohol-like. Mixing alcohol with the ADHD medicine ritalin, for example, can <a href="https://www.healthline.com/health/adhd/ritalin-and-alcohol#side-effects">increase the drug’s effect on the heart</a>, increasing your heart rate and the risk of a heart attack.</p> <p>Combining alcohol with ibuprofen can lead to a higher risk of stomach upsets and stomach bleeds.</p> <p>Alcohol can increase the break-down of certain medicines, such as <a href="https://www.sciencedirect.com/science/article/abs/pii/S0149763421005121?via%3Dihub">opioids, cannabis, seizures, and even ritalin</a>. This can make the medicine less effective. Alcohol can also alter the pathway of how a medicine is broken down, potentially creating toxic chemicals that can cause serious liver complications. This is a particular problem with <a href="https://australianprescriber.tg.org.au/articles/alcohol-and-paracetamol.html">paracetamol</a>.</p> <p>At its worst, the consequences of mixing alcohol and medicines can be fatal. Combining a medicine that acts on the brain with alcohol may make driving a car or operating heavy machinery difficult and lead to a serious accident.</p> <h2>Who is at most risk?</h2> <p>The effects of mixing alcohol and medicine are not the same for everyone. Those most at risk of an interaction are older people, women and people with a smaller body size.</p> <p>Older people do not break down medicines as quickly as younger people, and are often on <a href="https://www.safetyandquality.gov.au/our-work/healthcare-variation/fourth-atlas-2021/medicines-use-older-people/61-polypharmacy-75-years-and-over#:%7E:text=is%20this%20important%3F-,Polypharmacy%20is%20when%20people%20are%20using%20five%20or%20more%20medicines,take%20five%20or%20more%20medicines.">more than one medication</a>.</p> <p>Older people also are more sensitive to the effects of medications acting on the brain and will experience more side-effects, such as dizziness and falls.</p> <p>Women and people with smaller body size tend to have a higher blood alcohol concentration when they consume the same amount of alcohol as someone larger. This is because there is less water in their bodies that can mix with the alcohol.</p> <h2>What drugs can’t you mix with alcohol?</h2> <p>You’ll know if you can’t take alcohol because there will be a prominent warning on the box. Your pharmacist should also counsel you on your medicine when you pick up your script.</p> <p>The most common <a href="https://adf.org.au/insights/prescription-meds-alcohol/">alcohol-interacting prescription medicines</a> are benzodiazepines (for anxiety, insomnia, or seizures), opioids for pain, antidepressants, antipsychotics, and some antibiotics, like metronidazole and tinidazole.</p> <p>It’s not just prescription medicines that shouldn’t be mixed with alcohol. Some over-the-counter medicines that you shouldn’t combine with alcohol include medicines for sleeping, travel sickness, cold and flu, allergy, and pain.</p> <p>Next time you pick up a medicine from your pharmacist or buy one from the local supermarket, check the packaging and ask for advice about whether you can consume alcohol while taking it.</p> <p>If you do want to drink alcohol while being on medication, discuss it with your doctor or pharmacist first.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/223293/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/nial-wheate-96839"><em>Nial Wheate</em></a><em>, Associate Professor of the School of Pharmacy, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/jasmine-lee-1507733">Jasmine Lee</a>, Pharmacist and PhD Candidate, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>; <a href="https://theconversation.com/profiles/kellie-charles-1309061">Kellie Charles</a>, Associate Professor in Pharmacology, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a>, and <a href="https://theconversation.com/profiles/tina-hinton-329706">Tina Hinton</a>, Associate Professor of Pharmacology, <a href="https://theconversation.com/institutions/university-of-sydney-841">University of Sydney</a></em></p> <p><em>Image credits: Getty Images </em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/why-its-a-bad-idea-to-mix-alcohol-with-some-medications-223293">original article</a>.</em></p>

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"Do you hear it?": Worldwide hum global mystery baffles scientists

<p>A perplexing phenomenon known as "The Worldwide Hum" has been capturing the attention of scientists and citizens alike, as an unusual low-frequency noise continues to puzzle experts.</p> <p>This mysterious hum, first recorded in 2012, has been reported by thousands of people worldwide, sparking investigations, online discussions and even <a href="https://www.thehum.info/" target="_blank" rel="noopener">the creation of an interactive map</a> documenting instances of the enigmatic sound. As researchers strive to unravel the mystery, individuals share their experiences, raising questions about its origin and effects.</p> <p>Described as a low rumbling or droning sound, "the hum" is often likened to the idling of a car or truck engine. What makes this phenomenon particularly intriguing is that it is not universally heard, with reports of the hum being exclusive to certain individuals.</p> <p>Some claim it is more pronounced at night than during the day, and louder indoors than outdoors. One Reddit user even compared it to the low-frequency vibrations felt when a passenger jet flies overhead.</p> <p>Since its first documentation, more than 6,500 instances of the hum have been reported globally, with new cases continually emerging. The interactive user-generated World Hum Map and Database Project <span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">captures the experiences of those who have encountered the sound, providing a comprehensive overview of its widespread occurrence. In some regions, authorities such as the Environment Protection Authority (EPA) have conducted investigations, as was the case in the NSW Waverley Council ten years ago. Despite these efforts, the source of the hum remains elusive.</span></p> <p>Individuals affected by the mysterious noise often find solace in online communities, where they share their experiences and discuss possible explanations. Some describe feeling as though they are "going insane", and say that the psychological impact of the persistent hum is actually very severe.</p> <p>Facebook support groups have become a platform for individuals to connect, share anecdotes and speculate about the origin of the sound. Theories range from the mundane – such as the use of headphones causing collective tinnitus – to more complex environmental factors.</p> <p>While tinnitus, a symptom of auditory system issues, has been proposed as a potential explanation, it does not account for the collective experience of the hum. Various theories, including industrial plants, ocean waves, lightning strikes and the proliferation of mobile phone towers, have been suggested over the years. However, none of these explanations have gained widespread acceptance or provided a conclusive answer.</p> <p>Dr Glen MacPherson, who initiated the World Hum Map and Database Project, experienced the hum firsthand on Canada's Sunshine Coast. Having debunked the idea of "hum hotspots", Dr MacPherson theorises that the hum may be a subjective phenomenon, akin to tinnitus, originating from within the individual rather than an external source. His 11 years of research highlight the complexity of the mystery, challenging initial assumptions and pointing towards the need for further investigation.</p> <p>As "The Worldwide Hum" continues to captivate the curiosity of scientists and citizens worldwide, the quest for understanding remains elusive. While theories abound, the true origin of the hum remains unknown, leaving both experts and individuals alike intrigued by a phenomenon that transcends geographic boundaries and defies conventional explanations.</p> <p><em>Image: Getty</em></p>

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Hunt for Cinderella! Mystery shoe left at Prince Christian's party sparks search

<p>A mystery shoe left at Prince Christian's <a href="https://www.oversixty.co.nz/lifestyle/family-pets/from-child-to-adult-unseen-pics-of-prince-christian-mark-his-18th-birthday" target="_blank" rel="noopener">18th birthday party</a> inside Christianborg Palace has sparked a search for a real life Cinderella. </p> <p>In the hours after the ball, which saw royalty from around the world attend, the Danish royal household posted a photo of the gold stiletto that was left behind from one of the high profile party guests. </p> <p>The post read, "Is it Cinderella who forgot her shoe last night?"</p> <p>The caption continued, "When the guests at Her Majesty the Queen's gala dinner yesterday had gone home, this lonely stiletto shoe was left at Christiansborg Castle."</p> <p>"The owner is welcome to contact you to get it back."</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-permalink="https://www.instagram.com/p/CydeENrNum2/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/CydeENrNum2/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by DET DANSKE KONGEHUS 🇩🇰 (@detdanskekongehus)</a></p> </div> </blockquote> <p>The ball was attended by Crown Princess Mary and Crown Prince Frederik, along with Christian's younger siblings Princess Isabella, 16, Prince Vincent and Princess Josephine, both 12.</p> <p>His uncle Prince Joachim, who relocated to America in August, was also there with his wife Princess Marie and their three youngest children Count Felix, 21, Count Henrik, 14, and Countess Athena, 12.</p> <p>A number of future monarchs were also present including royals from Sweden, Norway, the Netherlands and Belgium.</p> <p>Thankfully, the owner of the shoe was found, with Anne-Sofie Tørnsø Olesen, from Denmark's Egedal region, coming forward to claim the golden stiletto. </p> <p>And it turns out, she left it at the palace on purpose after being inspired by the story of Cinderella who marries her prince after long search.</p> <p>"I thought it was a bit funny myself, and I talked to my family and friends about it before, and they agreed that I should do it," Tørnsø Olesen, 18, told local Danish publication Se &amp; Hør.</p> <p>"It's such a chance you won't get again."</p> <p>She said she was keen to get the shoe back because it was "a memory from a great evening".</p> <p>The lost shoe, by Danish brand Deichmann's Catwalk collection, sparked an immediate flurry of comments on the royal family's Instagram page.</p> <p>The shoe brand said, "If the princess comes from a long way, we will gladly give her a new pair".</p> <p><em>Image credits: Getty Images / Instagram </em></p>

Beauty & Style

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Cancer is rising in under-50s – but the causes are a mystery

<p><em><a href="https://theconversation.com/profiles/ashleigh-hamilton-1468163">Ashleigh Hamilton</a>, <a href="https://theconversation.com/institutions/queens-university-belfast-687">Queen's University Belfast</a></em></p> <p>Cancer is often thought of as a disease that mostly affects older people. But worrying new research shows that cancer in younger adults is a growing problem. The study found there’s been a nearly 80% increase in the number of under-50s being <a href="https://bmjoncology.bmj.com/content/2/1/e000049">diagnosed with cancer</a> globally in the last three decades.</p> <p>Also of concern are the types of cancers being seen in younger adults – with this latest study and previous research showing that cancers thought of as typical of older age groups are now increasingly being diagnosed in younger people. These include <a href="https://pubmed.ncbi.nlm.nih.gov/31105047/">bowel cancer</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/31331685/">stomach cancer</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/32144720/">breast cancer</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/30733056/">uterine cancer</a> and <a href="https://pubmed.ncbi.nlm.nih.gov/35053447/">pancreatic cancer</a>.</p> <p>This is worrying because some of these cancers – particularly <a href="https://www.cancerresearchuk.org/about-cancer/pancreatic-cancer/survival">pancreatic</a> and <a href="https://www.cancer.org/cancer/types/stomach-cancer/detection-diagnosis-staging/survival-rates.html">stomach</a> cancer – have low survival rates, due to the fact they’re often diagnosed at a late stage. Research has also shown that bowel cancer tends to be <a href="https://pubmed.ncbi.nlm.nih.gov/29564176/">diagnosed at a more advanced stage</a> in young people compared with older adults.</p> <p>While it’s clear from this latest study that cancer is becoming more common in those under 50, experts still aren’t entirely sure what’s causing this rise.</p> <h2>Early-onset cancer</h2> <p>The study investigated cancer cases in people under the age of 50 (termed “early-onset cancer”) from 204 countries and regions. The data analysed was collected between 1990 and 2019. The researchers were interested in knowing not only the incidence of early-onset cancer, but what types of cancer had the highest burden in under-50s.</p> <p>They found that in 2019, there were 3.26 million cases of early-onset cancer diagnosed worldwide – a 79% increase since 1990. The authors also predicted that by 2030, the number of under-50s diagnosed with cancer would increase by a further 31%.</p> <p>Breast cancer was the most common early-onset cancer in 2019, but incidences of prostate and throat cancers increased at the fastest rate since 1990. Liver cancer decreased the fastest over the same time period.</p> <p>The number of deaths due to early-onset cancers also increased from 1990 to 2019 – although less quickly than the rate of diagnosis, with 1.06 million deaths worldwide in 2019, an increase of 28%. The cancers with the highest number of deaths in 2019 were breast, lung, bowel and stomach cancers. The age group at greatest risk of early-onset cancer were those in their 40s.</p> <p>In 2019, early-onset breast cancer had the highest burden for women, while early-onset lung cancer the highest burden for men. Women were disproportionately affected in terms of death and poor health from early-onset cancer in low- and middle-income countries.</p> <p>The study also shows that while the highest number of early-onset cancer cases were in developed countries such as western Europe, North America and Australasia, many cases were also seen in low- and middle-income countries. Death rates were also higher in low- and middle-income countries.</p> <p>The main limitation of this paper is the variability of the data collected by different countries, making it difficult to measure its completeness. Nonetheless, it is still useful in getting a picture of global health.</p> <h2>Unknown causes</h2> <p>There’s no single explanation for why cancers are rising in under-50s.</p> <p>Some cancers in younger people happen as a result of a genetic condition – but these only <a href="https://aacrjournals.org/cancerres/article/80/16_Supplement/1122/641186">account for a small number of cases</a> (around 20%).</p> <p>Lifestyle factors such as the foods we eat, whether we drink alcohol or smoke, and being overweight are all linked to an <a href="https://www.cancer.gov/about-cancer/causes-prevention/risk">increased risk</a> of many types of cancer. Research indicates that these factors may be contributing to a rise in <a href="https://pubmed.ncbi.nlm.nih.gov/33524598/">early-onset colorectal cancer</a>, for example. Whether this is true for other types of early-onset cancer remains unknown.</p> <p>Some people affected by early-onset cancers may live healthy lifestyles. This suggests there are probably other reasons for the increase that have not yet been discovered.</p> <p>It’s clear from this research that the landscape of cancer is changing. While the incidence of early-onset cancers is increasing, cancer in this age group is still much less common than for those over-50. Early-onset cancers account for only around a tenth of <a href="https://www.cancerresearchuk.org/health-professional/cancer-statistics/incidence/age">new cases in the UK</a>. But though the numbers are still relatively low, this doesn’t mean the trend we’re seeing isn’t of concern.</p> <p>It will be crucial now to ensure there’s greater awareness of early-onset cancers. Most younger people, and even healthcare professionals, don’t necessarily put cancer at the top of the list when symptoms develop. It’s important for people to see their GP if they notice any new symptoms, as detecting cancer at an early stage leads to a better prognosis.</p> <p>Urgent research into early-onset cancer is also needed at a national and international level. The underlying causes are probably different depending on a person’s sex, ethnicity and where they live.</p> <p>On a personal level, there are many things you can do to reduce your risk of developing cancer. <a href="https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/can-cancer-be-prevented">Following a healthy lifestyle</a> remains important. This includes eating a healthy diet, stopping smoking, exercising regularly, reducing your alcohol intake, being safe in the sun and maintaining a healthy weight. If something doesn’t feel right with your body or you experience any new symptoms, it’s important to see a doctor as soon as you can.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/212834/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><a href="https://theconversation.com/profiles/ashleigh-hamilton-1468163"><em>Ashleigh Hamilton</em></a><em>, Academic Clinical Lecturer, Centre for Public Health, <a href="https://theconversation.com/institutions/queens-university-belfast-687">Queen's University Belfast</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/cancer-is-rising-in-under-50s-but-the-causes-are-a-mystery-212834">original article</a>.</em></p>

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Madonna rushed to intensive care

<p dir="ltr">Madonna was rushed to a hospital in New York and admitted into the ICU on Saturday after being found unresponsive. She has since been treated for a serious bacterial infection.</p> <p dir="ltr">The <em>Material Girl </em>was intubated for at least one night but is now reportedly out of the ICU, alert and recovering, according to Page Six.</p> <p dir="ltr">The singer had her daughter, Lourdes Leon, by her side during the entire ordeal.</p> <p dir="ltr">Madonna’s longtime manager, Guy Oseary, has released a statement on Instagram regarding the incident.</p> <p dir="ltr">“On Saturday June 24, Madonna developed a serious bacterial infection which led to a several day stay in the ICU,” he started the post.</p> <p dir="ltr">“Her health is improving, however she is still under medical care. A full recovery is expected,” he added.</p> <p dir="ltr">Oseary also announced that all of the singer’s current commitments including her upcoming world tour have been “paused” due to the medical emergency, however further details will be provided with new dates for the tour “as soon as we have them”.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/p/CuC6w1TPH_l/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/CuC6w1TPH_l/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by Guy Oseary (@guyoseary)</a></p> </div> </blockquote> <p dir="ltr">The “Celebration” tour highlighting her greatest hits and the 40th anniversary of her breakout single, <em>Holiday</em> was set to kick off on July 15 in Vancouver and wrapped up in Amsterdam on December 1.</p> <p dir="ltr">Fans and celebrities alike have sent their love and report for the recovering star in the comment section of Oseary’s post.</p> <p dir="ltr">“Hope she feels better very soon!” commented <em>New Girl</em> actor Zoey Deschanel.</p> <p dir="ltr">“Sending her so much love from us. ❤️❤️❤️” wrote Aussie actress Isla Fisher.</p> <p dir="ltr">“Omg sending her love and healing light! 🙏” commented Ariana Grande’s brother Frankie.</p> <p dir="ltr">“Please send her my love and support. I’ll be sending prayers for her healing ❤️❤️🙏🙏,” wrote one fan.</p> <p dir="ltr">“Health is everything. Take as much time as needed,” commented another.</p> <p dir="ltr"><em>Images: Getty</em></p>

Caring

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"A night in hospital and a trip to the burns unit later”: Concerned mum's warning against popular fruit

<p><em><strong>Warning: This article contains images that some readers may find distressing.</strong></em></p> <p>An Aussie mum has taken to the internet and shared photos of her son’s severe burns that came as a result of him playing with a popular fruit. “A night in hospital and a trip to the burns unit later.” She began in her Facebook post.</p> <p>Her son Otis was playing happily outside with a lime in the sunshine, but the next day horror ensued.</p> <p>“It wasn’t until the next day that we noticed a rash appeared.” The mother said.</p> <p>The parents had assumed the rash must’ve been an allergic reaction to the lime juice, however, the rash quickly developed into a “horrific burn,” she added.</p> <p>The parents took Otis to the hospital where they were informed their son was suffering from a condition called phytophotodermatitis.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-permalink="https://www.instagram.com/p/Cku5QH2thxE/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/Cku5QH2thxE/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by Tiny Hearts (@tinyheartseducation)</a></p> </div> </blockquote> <p>Phytophotodermatitis, more commonly known as margarita burn, is a little-known condition which causes burns to the skin when a chemical called furocoumarin reacts to sunlight.</p> <p>The chemical is found in limes, citrus fruit and some plants.</p> <p>“The small lime he had been innocently playing with - had now burnt his skin horrifically!“ The mum said. “If our story can help raise awareness into phytophotodermatitis at least something good has come out of our horrific experience!”</p> <p>The woman has urged parents to be on the lookout for this little-known skin condition.</p> <p>To minimise the risks of phytophotodermatitis, <a href="https://www.healthline.com/" target="_blank" rel="noopener">Healthline</a> suggests washing hands and other exposed parts of the skin immediately after being outdoors, wearing gloves when gardening, putting on sunscreen before going outdoors and wearing long-sleeved tops and pants in wooded areas.</p> <p>Photo credit: Getty</p>

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People with long COVID continue to experience medical gaslighting more than 3 years into the pandemic

<p><em><a href="https://theconversation.com/profiles/simran-purewal-1405366">Simran Purewal</a>, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>; <a href="https://theconversation.com/profiles/kaylee-byers-766226">Kaylee Byers</a>, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>; <a href="https://theconversation.com/profiles/kayli-jamieson-1431392">Kayli Jamieson</a>, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>, and <a href="https://theconversation.com/profiles/neda-zolfaghari-1431577">Neda Zolfaghari</a>, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a></em></p> <p>It’s increasingly clear that the <a href="https://www.worldometers.info/coronavirus/country/canada/">SARS-CoV-2 virus is not going away</a> any time soon. And for some patients, their symptoms haven’t gone away either.</p> <p>In January 2023, our team of researchers at the <a href="https://pipps.ca/">Pacific Institute on Pathogens, Pandemics and Society</a> published a <a href="https://pipps.cdn.prismic.io/pipps/bd160219-3281-4c5d-b8be-57c301e7f99b_Long+Covid+Brief+Feb+2023.pdf">research brief</a> about how people seek out information about long COVID. The brief was based on a scoping review, a type of study that assesses and summarizes available research. Our interdisciplinary team aims to understand the experiences of people with long COVID in order to identify opportunities to support health care and access to information.</p> <h2>Lingering long COVID</h2> <p>Long COVID (also called <a href="https://www.canada.ca/en/public-health/services/diseases/2019-novel-coronavirus-infection/symptoms/post-covid-19-condition.html">Post COVID-19 condition</a>) is an illness that occurs after infection with COVID-19, lasting weeks to months, and even years. First coined by a <a href="https://doi.org/10.1016%2Fj.socscimed.2020.113426">patient on Twitter</a>, the term also represents a collective movement of people experiencing the long-term effects of COVID-19 and advocating for care. <a href="https://science.gc.ca/site/science/sites/default/files/attachments/2023/Post-Covid-Condition_Report-2022.pdf">Around 15 per cent</a> of adults who have had COVID still have symptoms after three months or more.</p> <p>Long COVID affects systems <a href="https://doi.org/10.1016/j.socscimed.2021.114619">throughout the body</a>. However, symptom fluctuations and limited diagnostic tools make it challenging for health-care providers to diagnose, especially with <a href="https://doi.org/10.1038/s41579-022-00846-2">over 200 symptoms</a> that may present in patients. Perhaps because long COVID presents itself in many different ways, the illness has <a href="https://doi.org/10.1016/j.socscimed.2021.114619">been contested</a> across the medical field.</p> <p>To identify opportunities to reduce barriers to long COVID care, our team has explored how patients and their caregivers access <a href="https://pipps.cdn.prismic.io/pipps/bd160219-3281-4c5d-b8be-57c301e7f99b_Long+Covid+Brief+Feb+2023.pdf">information about long COVID</a>. We have found that one of the most significant barriers faced by patients is <a href="https://doi.org/10.1177/20552076211059649">medical gaslighting</a> by the people they have turned to for help.</p> <h2>Lack of validation leads to stigma</h2> <p><a href="https://doi.org/10.1136/bmj.o1974">Medical gaslighting</a> occurs when health-care practitioners dismiss or falsely blame patients for their symptoms. While new information about long COVID has become more readily available, some patients continue to face gaslighting and feel that their symptoms are <a href="https://doi.org/10.1016%2Fj.ssmqr.2022.100177">treated less seriously</a> by some health-care professionals.</p> <p>This dismissal can <a href="https://doi.org/10.1111/hex.13602">erode trust</a> in the health-care system and can also lead to <a href="https://doi.org/10.1111/hex.13518">stigma and shame</a>.</p> <p>Preliminary findings from our ongoing study with long COVID patients indicate that, when medical practitioners do not validate a patient’s condition, this extends into community networks of family and friends who may also dismiss their symptoms, contributing to further stigmatization at home.</p> <p>Medical gaslighting can present additional barriers to treatment, such as not being referred to specialists or long COVID clinics. This can, in turn, compound other symptoms such as fatigue, and <a href="https://doi.org/10.1192/bjo.2022.38">exacerbate the psychological symptoms of long COVID</a>, such as depression and anxiety.</p> <p>Medical gaslighting isn’t new. It has been documented by patients with other chronic conditions, such as <a href="https://doi.org/10.5772/intechopen.107936">myalgic encephalomyelitis or chronic fatigue syndrome</a>. And while this is common for patients with <a href="https://doi.org/10.1001/amajethics.2021.512">non-visible illnesses</a>, medical gaslighting is more commonly experienced by <a href="https://doi.org/10.1111/1467-9566.13367">women and racialized people</a>.</p> <p>Long COVID patients also note gender biases, as women with prolonged symptoms feel they are not believed. This is particularly worrisome, as studies have found that <a href="https://doi.org/10.1001/jama.2020.17709">women are disproportionately more likely to experience long COVID</a>.</p> <h2>Where do we go from here?</h2> <p>While long COVID information is constantly shifting, it’s clear that patients face many barriers, the first of which is having their illness minimized or disregarded by others. To ensure that patients have access to compassionate care, we suggest:</p> <p><strong>1. Educating physicians on long COVID</strong></p> <p>Because definitions of long COVID, and its presentation, vary widely, primary care physicians need support to recognize and acknowledge the condition. General practitioners (GPs) must also provide patients with information to help manage their symptoms. This requires actively listening to patients, documenting symptoms and <a href="https://doi.org/10.1136/bmj.m3489">paying close attention to symptoms that need further attention</a>.</p> <p>Training physicians on the full range of symptoms and referring patients to available supports would reduce stigma and assist physicians by reducing their need to gather information themselves.</p> <p><strong>2. Raise awareness about long COVID</strong></p> <p>To increase awareness of long COVID and reduce stigma, public health and community-based organizations must work collaboratively. This may include a public awareness and information campaign about long COVID symptoms, and making support available. Doing so has the potential to foster community support for patients and improve the mental health of patients and their caregivers.</p> <p><strong>3. Ensure information is accessible</strong></p> <p>In many health systems, GPs are <a href="https://doi.org/10.1186/s12913-019-4419-0">gatekeepers to specialists</a> and are considered trusted information sources. However, without established diagnostic guidelines, patients are left to <a href="https://doi.org/10.2196/37984">self-advocate</a> and prove their condition exists.</p> <p>Because of negative encounters with health-care professionals, patients turn to social media platforms, including long COVID <a href="https://doi.org/10.7861%2Fclinmed.2020-0962">online communities</a> on Facebook. While these platforms allow patients to validate experiences and discuss management strategies, patients should not rely only on social media given the <a href="https://doi.org/10.3389/fpubh.2022.937100">potential for misinformation</a>. As a result, it is crucial to ensure information about long COVID is multi-lingual and available in a wide range of formats such as videos, online media and physical printouts.</p> <p>The <a href="https://science.gc.ca/site/science/en/office-chief-science-advisor/initiatives-covid-19/post-covid-19-condition-canada-what-we-know-what-we-dont-know-and-framework-action">recent recommendations of the Chief Science Advisor of Canada</a> to establish diagnostic criteria, care pathways and a research framework for long COVID are a positive development, but we know patients need support now. Improving long COVID education and awareness won’t resolve all of the issues faced by patients, but they’re foundational to compassionate and evidence-based care.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/203744/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><em><a href="https://theconversation.com/profiles/simran-purewal-1405366">Simran Purewal</a>, Research Associate, Health Sciences, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>; <a href="https://theconversation.com/profiles/kaylee-byers-766226">Kaylee Byers</a>, Regional Deputy Director, BC Node of the Canadian Wildlife Health Cooperative; Senior Scientist, Pacific Institute on Pathogens, Pandemics and Society, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>; <a href="https://theconversation.com/profiles/kayli-jamieson-1431392">Kayli Jamieson</a>, Master's Student in Communication, Research Assistant for Pacific Institute on Pathogens, Pandemics and Society, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a>, and <a href="https://theconversation.com/profiles/neda-zolfaghari-1431577">Neda Zolfaghari</a>, Project Coordinator, Pacific Institute on Pathogens, Pandemics and Society, and the Pandemics &amp; Borders Project, <a href="https://theconversation.com/institutions/simon-fraser-university-1282">Simon Fraser University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/people-with-long-covid-continue-to-experience-medical-gaslighting-more-than-3-years-into-the-pandemic-203744">original article</a>.</em></p>

Caring

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9 medical reasons your short-term memory is getting worse

<p><strong>What is short-term memory?</strong></p> <p>Short-term memory is the type of memory you need to accomplish your immediate goals, explains Dr Patrick Lyden, chair of the department of neurology at Cedars-Sinai Hospital. That may be working your way through tasks during the workday, remembering someone’s name, email, or phone number, or recalling where you tossed your keys when you got home.</p> <p><strong>Where is it located in the brain?</strong></p> <p>When someone rattles off their phone number, you file it away in brain circuits that include the hippocampus (your memory centre) and the amygdala (your emotional hub). Depending on how important the short-term memory item may be (your address, someone you call all the time), it can be converted into long-term memory, says Dr Lyden.</p> <p><strong>How does short-term memory work?</strong></p> <p>Short-term memory isn’t just about being able to quickly recall new info; there are three phases. “You have to register the information, store the information, and retrieve the information,” says Dr Lyden. Registering means that you’re paying attention in the first place. Storing the info means you’ve filed it away in your brain. Retrieval is the ability to access the memory again. Any of these steps can break down, he says.</p> <p><strong>Is your memory okay?</strong></p> <p>Many people assume they have a memory problem when the explanation is something else entirely, says Dr Lyden. Maybe you’re not paying attention because you’re gazing at your phone or texting, for example. The first step to figuring out if something is going on is to “pay closer attention,” he says. Repeat the new information three times to commit it to memory.</p> <p><strong>When it may be time to worry</strong></p> <p>If you can’t pass the “pay attention test” despite repeating the information, your next step, advises Dr Lyden, is to determine if your problem is storing new memories or retrieving them. If you’re having a problem remembering a new acquaintance’s name, ask them to give you three choices – like Carrie, Lauren, or Janet. If your problem is storing new memories, you won’t be able to remember. But if your problem is retrieval, you’ll remember that her name is Janet once you hear the correct name.</p> <p>Having trouble with retrieving a short-term memory isn’t as serious as being unable to store them. “The storage problem is a serious problem, and you should see a neurologist,” he says.</p> <p><strong>Inactivity</strong></p> <p>Blood flow is good for your brain – it keeps it young. “Exercising boosts blood flow to your brain. If you stay active, you’ll have a better memory,” says Dr Daniel G. Amen, author of <em>Memory Rescue: Supercharge Your Brain, Reverse Memory Loss, and Remember What Matters Most</em>. Dr Lyden suggests daily exercise and it doesn’t have to be intense. “A one-kilometre run daily is better than a 10-kilometre run one day a week,” he says.</p> <p><strong>Substance abuse</strong></p> <p>According to Dr Amen, marijuana a toxin that impairs memory. “Marijuana lowers every area of the brain and ages it. On average, pot smokers have brains three years older than non-smokers,” he says. Alcohol abuse can also harm your memory.</p> <p><strong>Mental health conditions</strong></p> <p>People tend to miss their own depression. But if you’re suffering from depression, anxiety, or chronic stress, get help or your memory can also pay the price. “These conditions may all hurt the brain,” says Dr Amen. Getting relief will not only improve your life and outlook but save your brain.</p> <p><strong>Lack of sleep</strong></p> <p>When considering short-term memory loss causes, poor sleep is a big one. “If you don’t sleep seven hours a night or more, you’ll be in trouble. Your brain cleans itself at night. When you don’t get enough, it’s like the garbage collectors didn’t come to clean up,” says Dr Amen.</p> <p><strong>Dementia</strong></p> <p>Before you panic, there’s some good news: “The vast majority of people who are healthy will not have a degenerative neurological condition causing short-term memory loss,” says Dr Lyden. But dementia or Alzheimer’s is a possibility in some groups. If you’re over 60 and have risk factors like diabetes, high blood pressure, or obesity, then you may be more prone to problems and need to be evaluated, he says.</p> <p><strong>Medication</strong></p> <p>If you lead a healthy lifestyle, eat right, exercise, and go easy on alcohol and other substances that can harm memory, yet you still feel like your memory if failing, talk to your doctor about your medications – prescription and over-the-counter, advises Dr Lyden. Cholesterol drugs, painkillers, high blood pressure pills, and sleeping pills are among the drugs that can trigger memory issues.</p> <p><strong>Hypothyroidism</strong></p> <p>When you have an under-active thyroid, everything in your body runs slower. Your digestion will slow and you can become constipated; cell growth slows and can lead to hair loss; your metabolism becomes sluggish, triggering weight gain. And you may be plagued by muddied thinking or forgetfulness. Often, medication to restore thyroid hormones can help alleviate symptoms and help you feel better all over.</p> <p><strong>A poor diet</strong></p> <p>Inflammation is bad for your body and your brain. “The higher the inflammation levels in your body, the worse your memory will be,” says Dr Amen. Eating an anti-inflammatory diet, like the Mediterranean diet, and avoiding foods that increase it (highly processed foods, loads of sugar) is key. He also recommends taking fish oil and probiotics.</p> <p><strong>Lyme disease</strong></p> <p>Lyme disease is transmitted through a tick bite, and causes early symptoms like fever, chills, headache, and fatigue, according to the Centers for Disease Control and Prevention (CDC). Later on, without treatment, some people also may notice short-term memory problems. Dr Amen points out this may include trouble with attention, focus, and organisation. Keep in mind that the types of tick that carry the bacteria are not native to Australia and it’s not likely you can catch Lyme disease in Australia.</p> <p><strong>When to seek help</strong></p> <p>Along with the self-test mentioned earlier, think about how you perceive your short-term memory. Ask yourself: Is it getting progressively worse? Is it worse than 10 years ago? Are other people noticing a problem? “Those are things you should take seriously,” says Dr Amen.</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.co.nz/healthsmart/9-medical-reasons-your-short-term-memory-is-getting-worse-2?pages=1" target="_blank" rel="noopener">Reader's Digest</a>. </em></p>

Mind

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Know the signs of a heart attack this Heart Week

<p dir="ltr">Research conducted by Heart Smart Australia, an online health and wellbeing program, has revealed the concerning reality that only one third of Australians (38% of the 1,031 people surveyed) are able to recognise the symptoms of a heart attack, despite cardiovascular disease being attributed to <a href="https://www.heartfoundation.org.au/bundles/for-professionals/key-stats-cardiovascular-disease">25% of deaths in the country</a>. </p> <p dir="ltr">And during <a href="https://campaign.heartfoundation.org.au/heart-week">Heart Week</a>, which runs from May 1 to May 7, the organisation hopes to both raise awareness and educate everyone on the warning signs, from the obvious to the lesser known, to hopefully reduce an individual’s risk of heart disease.</p> <p dir="ltr">As explained on the official website for the initiative, Heart Week is “Australia’s national heart health awareness week” and “provides an opportunity for the Australian public and health professionals to start a conversation about heart health and take positive steps to reduce their heart disease risk.” </p> <p dir="ltr">Surprisingly, the generation with the least existing awareness are the Baby Boomers, with research showing that only 33% of them are typically able to recall all of the signs and symptoms.</p> <p dir="ltr">Roughly 98% of Australians were able to call one or more of the most common symptoms to mind, while only 55% were aware that fatigue is one of such signs. Fewer still - approximately 48% - could name nausea and vomiting as another. </p> <p dir="ltr">The numbers are far lower than ideal, and as leading cardiologist and Chief Medical Officer of Heart Smart Australia Dr Ross Walker explained, “heart attack can be a silent killer; therefore, it’s crucial that Australians are aware of all the symptoms, including the lesser-known ones such as fatigue, chest discomfort and vomiting.</p> <p dir="ltr">“If you experience any of these symptoms, it's important to seek medical attention immediately. We know that acting quickly reduces damage to the heart and increases chances of survival - it really is this important. Life or death!"</p> <p dir="ltr">Cardiovascular disease (otherwise known as CVD) accounts for a staggering one hospitalisation every single minute in Australia, so this Heart Week, Dr Walker is calling on everyone to get on top of their health, to learn the symptoms, and to make the necessary changes towards reducing the impact and risk of CVD. </p> <p dir="ltr">“Heart Health Week is the perfect opportunity for Australians to take stock of their heart health and make positive changes to their lifestyle,” he explained. “For example, we know that implementing some simple changes can reduce the risk profile for developing CVD. </p> <p dir="ltr">“Looking at things like participating in regular exercise, maintaining a healthy weight, not smoking, getting adequate sleep and eating a healthy, balanced diet are key."</p> <p dir="ltr">Some of Dr Walker’s main tips include forming strong social networks, not overlooking the importance of a healthy diet, exercising regularly, attending regular heart health check ups with medical professionals, and knowing the symptoms. </p> <p dir="ltr">“It’s not widely known, nor understood, but those with strong ties to friends and family fare better when it comes to lowering risk of heart disease. Regularly spend some guilt free time with loved ones - it’s for your heart,” he said. </p> <p dir="ltr">And as for diet, “Variety is key here. As well as a range of fruit and vegetables, including things like Omega 3’s and turmeric can work to decrease inflammation, a key risk factor for CVD.”</p> <p dir="ltr">For exercise, Dr Walker recommends a minimum of “5 or more active days”, with no less than two-and-a-half hours each week dedicated to physical activity.</p> <p dir="ltr">Heart health check ups are crucial, according to Dr Walker, who suggests that anyone over the age of 45 (or 30 for Indigenous Australians) should contact their doctor for a check up. </p> <p dir="ltr">“This check will include things like measuring blood pressure, cholesterol levels and assessing weight,” he noted. “Identifying risk works to pre-empt issues and is often an important preventative measure.” </p> <p dir="ltr">And when it comes to the symptoms, Dr Walker believes it to be imperative to recognise them, so that you can act immediately and get help as soon as possible if someone you know may be suffering from one, “as early treatment is strongly linked to better health outcomes”.</p> <p dir="ltr">Those all-important symptoms include chest pains - pressure and tightness - as well as dizziness and light-headedness, nausea or vomiting, indigestion, sweat, an unusually pale complexion, difficulty breathing and shortness of breath, and palpitations. </p> <p dir="ltr">Additionally, when dealing with a suspected heart attack in females, it’s important to watch out for breathlessness and general unwellness, tightness and discomfort of the arms, chest pains that are reminiscent of burning and trapped wind, as well as upper back pain and pressure in the area. </p> <p dir="ltr">For more information, and to learn more about the education and support on offer, head over to Heart Smart Australia’s official website: <a href="https://heartsmartaustralia.com/">https://heartsmartaustralia.com/</a> </p> <p dir="ltr"><em>Images: Getty</em></p>

Body

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13 Titanic mysteries that may never be solved

<p><strong>Was it even the Titanic?</strong></p> <p>Everyone agrees that a luxury liner set sail on April 10, 1912, and sank five days later, taking the lives of around 1500 of the 2223 passengers aboard. But that’s pretty much where the consensus ends. Some insist the ship that sank wasn’t the Titanic, but rather, the nearly identical R.M.S. Olympic. </p> <p>As the story goes, the Olympic had been damaged in an accident the year before, but in order to score a bigger insurance payoff, the ships’ common owners passed off the Olympic as the Titanic and then deliberately sank it. While there are lots of holes in this Titanic theory, serial numbers found on parts of the ship that didn’t sink support it.</p> <p><strong>Did a fire actually seal the ship's fate?</strong></p> <p>A recent documentary offers credible evidence that the Titanic (let’s just call it that, for argument’s sake) had been damaged by a coal fire, which had been raging for three weeks before the ship even set sail. </p> <p>The damage would have weakened the hull of the ship, thus hastening the ship’s sinking when it collided with an iceberg. (If it collided with an iceberg, which is another Titanic mystery we discuss below.)</p> <p><strong>Why was the captain speeding?</strong></p> <p>For decades, people believed that Captain Smith was speeding through the iceberg-heavy waters of the North Atlantic because he wanted the Titanic to cross the Atlantic faster than her sister ship, the Olympic. </p> <p>But in 2004, the Geological Society of America published an academic paper by engineer Robert H. Essenhigh with a different theory: It claimed the real reason the Titanic’s captain was speeding was to burn coal as quickly as possible in order to control the coal fire mentioned above.</p> <p><strong>What caused the ship to break into two pieces?</strong></p> <p>On September 1, 1985, oceanographer Robert Ballard discovered the wreckage four kilometres below the ocean surface, along with the surprising news that the ship had broken in two before sinking. Previously, everyone had thought that the ship sank intact after colliding with an iceberg while speeding recklessly through icy waters near the coast of Newfoundland. </p> <p>Ballard’s discovery led to a new theory: that the ship’s splitting into two pieces, which “may have been the difference between life and death,” was the result of design flaws and the skimping on quality materials by the owners and/or builders.</p> <p><strong>Did a torpedo sink the Titanic?</strong></p> <p>Most believe that the Titanic sank after hitting an iceberg on April 14 (regardless of other contributing factors). But not everyone. Some think that the Titanic was torpedoed by a German U-boat. This theory doesn’t seem all that far-fetched considering that three years later in 1915, a German U-boat did sink a passenger ship, the Lusitania. </p> <p>However, it’s possible that torpedo theorists are confusing the Titanic with the Lusitania. It’s also possible that they’re confusing the Titanic with the Olympic, which had sustained damage after colliding with a military vessel in 1911. Still, the presence of several other ships in the vicinity of the Titanic’s sinking leaves the question open.</p> <p><strong>Was there even an iceberg?</strong></p> <p>Assuming the Titanic didn’t collide with, and wasn’t torpedoed by, another ship, it’s safe to believe that it hit an iceberg, right? Not necessarily. Professional mariner Captain L.M. Collins maintains that if the Titanic had hit an iceberg, it would have gone down in mere minutes. </p> <p>Instead, Collins and his followers believe that the Titanic must have hit a hidden floe of “pack ice” (multi-year-old sheets of ice floating near the ocean surface) that had made its way into the Atlantic from the Arctic Ocean. Collins points out discrepancies in eyewitness accounts, which may actually be due to various natural optical illusions. If only the crew had binoculars, right?</p> <p><strong>Why didn't the crew have binoculars?</strong></p> <p>Surely, if the crew had binoculars, they would have seen the danger in time to change course. But the Titanic’s entire supply of binoculars was locked away in a storage compartment. And a crew member who had been transferred off the ship just before it set sail had the key. </p> <p>The crew member later claimed he “forgot” to hand over the key. But did he forget? Or did he deliberately hold onto it? And if so, was it to further the insurance fraud mentioned above? Or was it something else entirely?</p> <p><strong>If there was a warning, why didn't anyone take it seriously?</strong></p> <p>Even without binoculars, the Titanic might have had time to change course before its collision if someone had warned the crew. But here’s the thing: Someone did warn the crew. An hour before the collision, a nearby ship, the S.S. Californian, had radioed to say that it had been stopped by “dense field ice.” </p> <p>However, the Titanic’s radio operator, Jack Phillips, never conveyed the warning to Captain Smith. Some say the message was deliberately conveyed as “non-urgent,” but we will never know for sure since Phillips went down with the ship.</p> <p><strong>Did the Californian have something to do with it?</strong></p> <p>This cruise liner was less than 20 kilometres away from where the Titanic sank. It sent a warning to the Titanic about the dangerously icy conditions, which may have been relayed as a non-urgent matter. </p> <p>Later, the Californian crew reportedly ignored the Titanic’s distress signals, although they claimed they were not aware of those signals because their radio operator had gone off duty. Did the Californian really not notice what was happening within plain view?</p> <p><strong>The "third" ship</strong></p> <p>The Californian may not have been the only ship that ignored the Titanic’s distress signals. A Norwegian ship, the Samson, may have been nearby as well. </p> <p>In fact, some believe that the Samson was closer to the Titanic than the Californian but ignored her distress signals in order to avoid prosecution for illegal seal-hunting. This is a popular theory among defenders of the Californian’s captain, but whether it’s true remains a mystery.</p> <p><strong>Did J.P. Morgan plan the whole thing?</strong></p> <p>Some who believe the Titanic took the place of the damaged Olympic blame financier J.P. Morgan, who was one of the owners of the company that owned both ships. Morgan was one of the wealthiest people on the planet at the time, and he wielded considerable power. </p> <p>In addition, he was a last-minute no-show on the Titanic’s sole voyage. Why did Morgan – and his entire family – not end up on the ship? Did he know what was going to happen? Did he plan it?</p> <p><strong>Was it a murder plot?</strong></p> <p>Some believe the sinking had nothing to do with insurance money, but rather that J.P. Morgan engineered the sinking to kill off his rivals: Jacob Astor, Isidor Straus, and Benjamin Guggenheim, all of whom perished aboard. But how did Morgan plan to pull it off? Neither the insurance theory nor the murder theory takes that into account.</p> <p><strong>Why weren't there enough lifeboats?</strong></p> <p>“No matter what caused the Titanic to sink, such a massive loss of life could probably have been avoided if the ship had carried sufficient lifeboats for its passengers and crew,” notes History.com. So then why did the uber-luxury liner have only 20 lifeboats, the legal minimum? Why did the ship’s owners decide to ignore recommendations to carry 50 per cent more lifeboats? </p> <p>If the sinking were “merely” an insurance scam, how can the devastating lack of lifeboats be explained? This seems to dovetail more with a murder plot. But it also could be nothing more than cost-cutting on the part of the ship’s owners.</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.co.nz/food-home-garden/13-titanic-mysteries-that-may-never-be-solved-2?pages=1" target="_blank" rel="noopener">Reader's Digest</a>. </em></p>

Cruising

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“Game-changer”: Michael J Fox shares huge medical news

<p dir="ltr">Michael J Fox has shared news of a medical breakthrough into Parkinson’s disease.</p> <p dir="ltr">The 61-year-old – who was diagnosed with the disease in 1991 – was thrilled to share the news, despite suffering a “terrible year”.</p> <p dir="ltr">Fox told <a href="https://www.statnews.com/2023/04/12/michael-j-fox-parkinsons-biomarker/" target="_blank" rel="noopener"><em>Stat News</em></a> that he had broken multiple bones after a fall, including some in his hand and face, but has said that in some ways he is “feeling better”.</p> <p dir="ltr">Despite his own personal battle, the <em>Back to the Future</em> star was overjoyed to share the breakthrough in Parkinson’s research.</p> <p dir="ltr">The study – funded by Fox’s charity organisation that aims to find a cure for Parkinson’s – found that a key Parkinson's pathology can now be identified by examining spinal fluid from living patients, allowing earlier intervention.</p> <p dir="ltr">“It’s all changed. It can be known and treated early on. It’s huge,” he said</p> <p dir="ltr">“This is the thing. This is the big reward. This is the big trophy.”</p> <p dir="ltr">The findings, published in <em>The Lancet Neurology</em>, are the result of a 1,123-person study that Fox’s foundation has put hundreds of millions of dollars into since it began in 2010.</p> <p dir="ltr">An editorial in the medical journal has also called this research “a game-changer in Parkinson’s disease diagnostics, research, and treatment trials”.</p> <p dir="ltr">In late 2022 the actor opened up about his struggle with Parkinson’s in his emotional acceptance speech for the <a href="https://www.oversixty.co.nz/health/caring/michael-j-fox-reveals-more-details-about-his-struggle-with-parkinson-s" target="_blank" rel="noopener">Jean Hershel Humanitarian Award</a>.</p> <p dir="ltr">In the speech he said that the hardest part “was grappling with the certainty of the diagnosis and the uncertainty of the situation,” but has since felt relieved after an “outpouring of support” from the public and his peers.</p> <p><em>Image: Frazer Harrison for Getty Images</em></p>

Caring

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Mum of four saved by her smartwatch

<p dir="ltr">Ricki-Lee Wynne was gifted a smartwatch from her husband for her 40th birthday and she believes that without it, she wouldn’t be alive today.</p> <p dir="ltr">"There's no doubt that my smartwatch saved my life," she told 9news.com.au.</p> <p dir="ltr">Months prior to receiving the watch, Wynne had been experiencing strange health problems. </p> <p dir="ltr">"I was getting a pain over my shoulder blades and it hurt each time I breathed in," she said.</p> <p dir="ltr">Doctors were confused and Wynne was in and out of hospital having several X-rays, scans and blood tests in an attempt to find the underlying issue.</p> <p dir="ltr">Wynne also had an echocardiogram to test the functioning of her heart, all of which appeared normal. </p> <p dir="ltr">"The doctors were not sure what it was. They thought it could be a low-grade blood cancer," she said. </p> <p dir="ltr">The pain subsided for a little while but soon enough Wynne’s breathing problems returned. </p> <p dir="ltr">"I woke up one day and I couldn't breathe properly. I was just walking into work and I was thinking, 'Gosh, I can't get enough air into my lungs,'" she said.</p> <p dir="ltr">"I couldn't walk from one side of the room to the other without being short of breath.</p> <p dir="ltr">"I went to my GP and had an x-ray done, but nothing showed up.”</p> <p dir="ltr">That’s when Wynne noticed her smartwatch was acting up. </p> <p dir="ltr">"I'd been struggling with my watch for days to try and get the heart rate to show up," she said. </p> <p dir="ltr">The heart rate function of her smartwatch had never been an issue before, but now it was struggling to pick it up. </p> <p dir="ltr">"It was saying you need to change the position to measure a pulse," she said.</p> <p dir="ltr">"My chest was also feeling kind of wobbly for a couple of nights when I went to bed.”</p> <p dir="ltr">Despite her X-ray showing coming up clear, Wynne said she went back to see her GP and told him she was worried something was really wrong.</p> <p dir="ltr">"I just said to him, 'Even my heart rate isn't right, look at my watch,' and I showed it to him.”</p> <p dir="ltr">Wynne’s GP sent her off for an ECG which showed her heart rate had dropped to just 29 beats per minute, a major cause for concern. </p> <p dir="ltr">"As soon as I had the ECG, I had the doctor call me back and say you need to go straight to Box Hill Hospital," she said.</p> <p dir="ltr">"I was told at the hospital that if I hadn't come in I would have just died in my sleep.</p> <p dir="ltr">"I would not have woken up and my heart would have stopped.”</p> <p dir="ltr">Wynne was then fitted with an emergency pacemaker and eventually diagnosed with a rare auto-immune disorder called sarcoidosis, a condition that causes inflammation in different parts of the body, most commonly the lungs. </p> <p dir="ltr">Doctors believe Wynne's sarcoidosis moved from her lungs to her heart, causing her to become extremely ill. </p> <p dir="ltr">She still has the pacemaker in and combined with medication, her health has improved significantly. </p> <p dir="ltr">It’s safe to say Wynne won’t be taking off her smartwatch any time soon.</p> <p dir="ltr"><em>Image credit: Shutterstock</em></p>

Technology

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F1 legend shares rare update Michael Schumacher

<p>Formula 1 icon Eddie Jordan has shared a health update about his close friend Michael Schumacher, saying the motorsport legend is “there, but not there” as mystery continues to surround his health.</p> <p>Schumacher, 54, has not been seen or heard from for nearly ten years after his horror ski crash in 2013.</p> <p>He was left with a severe brain injury and in a medically induced coma.</p> <p>Mystery surrounds his condition as his family has imposed a strict “family only” rule on who can visit him.</p> <p>It came as Michael’s son Mick followed in his dad’s footsteps into F1.</p> <p>Unfortunately, 23-year-old Mick struggled and lost his race seat at the end of 2022 after a series of crashes for the Haas team.</p> <p>Eddie was denied a visit to see Michael but has been in contact with Mick.</p> <p>The F1 star said his “love” for the seven-time world champion “still lasts and will always do so while I’m able to draw breath.” when speaking to sports betting firm OLBG.</p> <p>Last year, he revealed his son Mick had reached out to him.</p> <p>“As far as I’m concerned, I was touched by it and the reason I was touched by it was because it can’t be easy knowing that your father is not able to be part of the family, he’s there but he’s not there,” Jordan said.</p> <p>Jordan revealed that Mick spoke highly of his father while he was enduring his own struggles in F1.</p> <p>“It touched me because I felt so much about Michael, I went out of my way to find him, give him his first chance in Spa, didn’t last very long but that love for him still lasts and will always do so while I’m able to draw breaths,” Eddie said.</p> <p>Mick was dropped by Haas in favour of veteran driver Nico Hulkenberg for 2023 and is now a reserve driver at Mercedes.</p> <p>Mick will be backing up Sir Lewis Hamilton and George Russell, potentially stepping in for them if they have to miss a race.</p> <p>Eddie believes Mick has it in him to find his way back into a full-time race seat.</p> <p>“He’s been dropped for somebody else, and that’s a tough decision, he has another fight to come back and to make his name, climb up that ladder again,” Eddie said.</p> <p>“I’m quite sure he will do it.”</p> <p>Jordan also revealed Michael named his son after racing champion Mick Doohan, saying Mick was given his name “as a mark of respect” to Doohan.</p> <p>“Mick Schumacher isn’t named after his dad like a lot of people seem to think,” he said.</p> <p>“Mick Schumacher is named after a person who his father, Michael, was in total awe of, a sportsman who had won five world titles back to back with Honda.</p> <p>“And that is no other than Mick Doohan.</p> <p>“As a mark of respect, Michael Schumacher called his son Mick.”</p> <p>Last year, Jordan revealed that Michael’s wife denied him permission to visit Schumacher after his horror skiing accident.</p> <p>His wife Corinna keeps his health journey a closely guarded secret.</p> <p>Corinna prefers to treat her husband privately at their home in Geneva, Switzerland, with ex-Ferrarri boss Jean Todt, one of the only people allowed to see him outside his immediate family.</p> <p>Jordan said he contacted Corinna, who was once the girlfriend of his team’s driver Heinz Harold Frentzen.</p> <p>Jordan told the Irish Daily Mirror, “I reached out and one stage asked was it appropriate and did I think we should go and visit him.</p> <p>“The answer was no. No visitations for anyone at that moment except the actual direct family.</p> <p>“However, since then, young Mick Schumacher – Michael’s son – has reached out to me, and he has been extraordinary.”</p> <p><em>Image credit: Getty</em></p>

Caring

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Woman spots dead husband in restaurant's new promo video

<p>A seemingly innocent promotional Facebook advertisement has prompted a slew of theories online, after a woman claims to have seen her dead husband sitting in a restaurant. </p> <p>An Indian restaurant by the name of Spice Cottage, located in West Sussex in the UK, has been flooded with social media comments after posting a video of their bustling business. </p> <p>The video shows happy diners tucking into meals as waiters attend to customers in the clip, which ends with a round of applause for the staff. </p> <p>After the video was shared to Facebook, a woman by the name of Lucy Watson commented a strange question, asking, "How old is the footage? My late husband and his son are on the first shot and he died in 2014??"</p> <p>A reply from the restaurant said, "Hi Lucy, sorry to hear this. This footage was recorded last week.'"</p> <p>The post has now amassed hundreds of comments from social media users, who swapped theories about the bizarre mystery. </p> <p>One person demanded an update from Ms Watson on her husband's death, while others chose to look on the lighter side as the jokes rolled in. </p> <p>One Facebook user said, "He wasn't dead. He was just in a korma."</p> <p> </p> <p>Another wrote, "I was there on this day and the flat bread that I ordered arrived after our main course, it was my late naan."</p> <p>Both Ms Watson and Spice Cottage have yet to comment further on the mystery. </p> <p><em>Image credits: Facebook</em></p>

Family & Pets

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Reward in mystery murder of billionaire couple tops $52 million

<p>The deaths of Canadian billionaires Barry and Honey Sherman have been a mystery right from the start.</p> <p>On December 15, 2017, a realtor giving a tour of the couple's Toronto mansion around midday discovered their bodies, fully dressed, beside their indoor basement swimming pool.</p> <p>They were semi-seated side by side, with belts tied around their necks and attached to the railing of the indoor pool according to police. Barry Sherman was 75 and his wife Honey was 70.</p> <p>The story made headlines across the globe, as police called the deaths suspicious.</p> <p>Theories have swirled about who might have wanted to kill the founder of Canadian generic drug giant Apotex and his philanthropic wife – being one of Canada's richest couples.</p> <p>Investigators have worked to connect the dots however, five years later, no arrests have been made. On this week's anniversary of the killings, the Shermans' son offered an additional $25 million (A$37 million) for information leading to an arrest.</p> <p>The reward is now $52 million.</p> <p>"This week marks the five-year anniversary since my parents were murdered in their home. Every day since then has been a nightmare. I have been overwhelmed with pain, loss, and sorrow and these feelings only continuously compound," Jonathon Sherman said in a statement announcing the reward money.</p> <p>"Closure will not be possible until those responsible for this evil act are brought to justice," he added.</p> <p>The victims' prominence meant the case was high profile from the start. At the time of his death, Forbes estimated Barry was worth $4.5 billion.</p> <p>The Shermans' wealth, vast investments and philanthropy work saw them cross paths with Canada's business and political elites, their funeral was attended by thousands of people, including Prime Minister Justin Trudeau and Kathleen Wynne, premier of the province of Ontario.</p> <p>At the service an emotional Jonathon Sherman took the stage, with his three sisters, and slammed speculation that their parents died by suicide.</p> <p>Police later concluded someone had killed them, only six weeks after the bodies were found, Toronto police announced a review of evidence showed they were victims of a homicide, saying they believed the couple was targeted.</p> <p>With no forced signs of entry to the property, it's possible someone had a key, had access to the lockbox that held the keys or was known to the couple, Gomes said.</p> <p>In 2021, police asked for help identifying a shadowy suspect.</p> <p>After years of silence, police made a shocking announcement on the fourth anniversary of the couple's deaths last year, sharing a video of a shadowy person caught on security video walking on the snow-covered sidewalks in the couple's North York neighborhood.</p> <p>The Sherman children say the lack of answers adds to their grief. It's been five years since the murders and there have been no major developments. True crime podcasts have even have tried to unravel intrigue surrounding the deaths.</p> <p>In a statement to the CBC, her brother, Jonathon Sherman, echoed the same sentiment, saying the family will never get closure until the killer is brought to justice.</p> <p>The siblings reminded the public of the $52 million in reward money and pleaded for anyone with information to contact the Toronto Police Service.</p> <p><em>Image: AP</em></p>

Legal

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Jennifer Hawkins builds opulent home for mystery client

<p dir="ltr">Former Miss Universe Jennifer Hawkins and her husband Jake Wall are building a mega mansion in the exclusive suburb of Whale Beach - but it’s not for them.</p> <p dir="ltr">The couple, who own design and construction firm J-Group, are reportedly building the large home for a mystery client who bought it for just under $30 million, per <em><a href="https://www.realestate.com.au/news/pictures-show-epic-scale-of-jennifer-hawkins-30m-whale-beach-mansion/" target="_blank" rel="noopener">realestate.com.au</a></em>.</p> <p dir="ltr">A 1950s home that sat on the 3200-square-metre lot was knocked down last year, with plans already approved by the local council for a three-storey, five-bedroom house with a gym, yoga room, theatre, half-basketball court, sauna and a four-car garage, to take its place.</p> <p><span id="docs-internal-guid-220550e2-7fff-2957-05a6-13576cba0a5d"></span></p> <p dir="ltr">Before the celebrity couple had plans for it, the sprawling block already had a taste of fame, with the double block once belonging to the soprano singer Joan Sutherland.</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/reel/ChRJd4Xpw7N/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/ChRJd4Xpw7N/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by J GROUP PROJECTS (@jgroupprojects)</a></p> </div> </blockquote> <p dir="ltr">Back in February, the couple’s company shared a rendered image of what the Whale Beach home would look like, complete with views of the waters of Dolphin Point.</p> <p dir="ltr">Wall and Hawkins have been active in the property world, having purchased a $6 million ‘knockdown’ in Terrigal, on the NSW Central Coast.</p> <p dir="ltr">In 2020, the couple offloaded a Newport property for an eye-watering $24.5 million to Mike Cannon Brookes, the co-CEO and co-founder of Atlassian.</p> <p dir="ltr"><span id="docs-internal-guid-20c398e9-7fff-568a-d2d4-af9dc187f976"></span></p> <p dir="ltr"><em>Image: Instagram</em></p>

Real Estate

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What’s so special about the Mona Lisa?

<p>Every day, <a href="https://www.nytimes.com/2018/04/27/arts/design/mona-lisa-instagram-art.html">thousands</a> of people from around the world crowd into a stark, beige room at Paris’s Louvre Museum to view its single mounted artwork, Leonardo da Vinci’s Mona Lisa. </p> <p>To do so, they walk straight past countless masterpieces of the European Renaissance. So why does the Mona Lisa seem so special? </p> <h2>The mystery of her identity</h2> <p>The story told by one of Leonardo’s first biographers, Giorgio Vasari, is that this oil portrait depicts Lisa Gherardini, second wife of a wealthy silk and wool merchant Francesco del Giocondo (hence the name by which it is known in Italian: La Gioconda). </p> <p>Leonardo likely commenced the work while in Florence in the early 1500s, perhaps when he was hoping to receive the commission to take on a massive wall painting of <a href="https://en.wikipedia.org/wiki/The_Battle_of_Anghiari_(Leonardo)">The Battle of Anghiari</a>.</p> <p>Accepting a portrait commission from one of the city’s most influential, politically-engaged citizens might well have helped his chances. A recently discovered marginal note by Agostino Vespucci, <a href="https://web.archive.org/web/20131105050239/http://www.ub.uni-heidelberg.de/Englisch/news/monalisa.html">one-time assistant to the diplomat and writer Niccolò Machiavelli,</a> records that Leonardo was working on a painting of “Lisa del Giocondo” in 1503.</p> <p>The Italian painter Raphael, a great admirer of Leonardo, leaves us a sketch from around 1505-6 of what seems to be <a href="https://www.wga.hu/frames-e.html?/html/r/raphael/7drawing/3/09drawin.html">this work</a>. When Leonardo later moved to France in 1516, he took this still unfinished work with him. </p> <p>However, art scholars have increasingly voiced doubts about whether the image in the Louvre can indeed be Vasari’s Lisa, for the style and techniques of the painting match far better Leonardo’s later work from 1510 onwards. </p> <p>Additionally, a visitor to Leonardo’s house in 1517 recorded seeing there a portrait of “a certain Florentine woman, done from life,” made “at the instance of the late magnificent Giuliano de Medici.” Medici was Leonardo’s patron in Rome from 1513 to 1516. Was our visitor looking at the same image Vasari and our marginal diarist describe as Lisa, or another portrait of a different woman, commissioned later? </p> <p>All in all, just who we are seeing in the Louvre remains one of the work’s many mysteries.</p> <h2>A portrait stripped bare</h2> <p>In comparison to many contemporary images of the elite, this portrait is stripped of the usual trappings of high status or symbolic hints to the sitter’s dynastic heritage. All attention is thus drawn to her face, and that enigmatic expression. </p> <p>Before the 18th century, emotion was more commonly articulated in painting through gestures of the hand and body than the face. But in any case, depictions of individuals did not aim to convey the same kinds of emotions we might look for in a portrait photograph today — think courage or humility rather than joy or happiness.</p> <p>Additionally, a hallmark of elite status was one’s ability to keep the passions under good regulation. Irrespective of dental hygiene standards, a broad smile in artworks thus generally indicated ill-breeding or mockery, as we see in Leonardo’s own study of Five Grotesque Heads.</p> <p>Our modern ideas about emotions leave us wondering just what Mona Lisa might have been feeling or thinking much more than the work’s early modern viewers likely did.</p> <h2>A 20th century phenomenon</h2> <p>In fact, there is a real question as to whether anyone before the 20th century thought much about the Mona Lisa at all. The historian <a href="https://books.google.com.au/books/about/Becoming_Mona_Lisa.html?id=L_3fPAAACAAJ&amp;source=kp_book_description&amp;redir_esc=y">Donald Sassoon has argued that much of the painting’s modern global iconic status</a> rests on its widespread reproduction and use in all manner of advertising.</p> <p>This notoriety was “helped” by its theft in 1911 by former Louvre employee, <a href="https://www.imdb.com/title/tt1816681/">Vincenzo Peruggia</a>. He remarkably walked out of the museum one evening after closing time with the painting wrapped in his smock coat. He spent the next two years with it hidden in his lodgings.</p> <p>Shortly after its return, the Dadaist Marcel Duchamp used a postcard of the Mona Lisa as the basis for his 1919 ready-made work, LHOOQ, initials that sound in French as “she has a hot ass”.</p> <p>Although not the first, it is perhaps among the best known examples of Mona Lisa parodies, along with <a href="https://web.archive.org/web/20091028014015/http://www.studiolo.org/Mona/MONA14.htm">Salvador Dali’s Self Portrait as Mona Lisa, 1954</a>.</p> <h2>Cultural furniture</h2> <p>From Duchamp and Dali, we have increasingly seen the Mona Lisa used as a trope. Balardung/Noongar artist <a href="https://artsearch.nga.gov.au/detail.cfm?irn=167350">Dianne Jones has reprised the work in her inkjet photographic portraits of 2005</a>, which are less pointed in their swipe at white European art and more luminous in their appropriation of Mona Lisa’s sense of dream-like plenitude. </p> <p>The painting appears as cultural furniture in the <a href="https://www.telegraph.co.uk/music/news/apeshit-beyonce-jay-zs-new-video-reinvented-louvre/">recent music video Apeshit, 2019, by Beyoncé and Jay Z</a>, in which they romp across the Louvre backed by a troupe of scantily clad dancers, striking Lady Hamilton-like poses in front of famous works of art.</p> <p>Apeshit itself closely imitates earlier works of contemporary high culture, not least French New Wave film director Jean-Luc Godard’s Bande à Part (Band of Outsiders), 1964, in which three friends, including Mona Lisa-like Anna Karina (Godard’s famous muse), meet up and run through the Louvre in record time.</p> <p>Meanwhile, the <a href="http://www.openculture.com/2018/03/when-german-performance-artist-ulay-stole-hitlers-favorite-painting.html">notorious theft of a work of art by German performance artist Ulay</a> in 1976, in which he removed the most famous (and kitsch) painting in the National Gallery in Berlin, Carl Spitzweg’s 1839 portrait of The Poor Poet, was a reprise of the theft of the Mona Lisa in 1911.</p> <p>Many contemporary artists have rubbished all the reverence surrounding bucket-list art visits such as that to the Mona Lisa. </p> <p>Recently, Belgian art provocateur Wim Delvoye (whose shit-producing machine, Cloaca, 2000, is one of the centrepieces of Hobart’s Museum of Old and New Art) installed Suppo (2012), a giant steel corkscrew suppository, under the Louvre’s central glass entry pyramid. This made it the first sighting of art in the museum to which the Mona Lisa’s visitors flock.</p> <p>Still, the mysteries of the Mona Lisa look set to intrigue us for years to come. It is precisely the breadth and depth of possible interpretations that makes her special. Mona Lisa is whoever we want her to be - and doesn’t that make her the ultimate female fantasy figure?</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://theconversation.com/whats-so-special-about-the-mona-lisa-117180" target="_blank" rel="noopener">The Conversation</a>. </em></p>

Art

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Researchers puzzled by results of anti-inflammatory medications for osteoarthritis

<p>Researchers in the US are calling for a re-evaluation of the way some well known painkillers are prescribed after research showed they may actually lead to a worsening of inflammation over time in osteoarthritis-affected knee joints.</p> <p>NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) such as ibuprofen and naproxen are designed to reduce inflammation for the estimated 2.2 million Australians suffering from the sometimes debilitating effects of osteoarthritis.</p> <p>Osteoarthritis is a degenerative condition affecting joints in the body – most commonly hips, knees, ankles, spine and hands – which results from the degradation of cartilage on the ends of bones within the joints. As the cartilage wears away, the bones rub together resulting in swelling, pain and restricted movement.</p> <p>To combat this pain and swelling, NSAIDs are commonly prescribed, however the long-term impact of this type of medication is unclear, including its effect on the progression of the condition.</p> <p>“To date, no curative therapy has been approved to cure or reduce the progression of knee osteoarthritis,” said the study’s lead author, Johanna Luitjens, from the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. “NSAIDs are frequently used to treat pain, but it is still an open discussion of how NSAID use influences outcomes for osteoarthritis patients.</p> <p>Surprisingly the report says: “…the impact of NSAIDs on synovitis, or the inflammation of the membrane lining the joint, has never been analysed using MRI-based structural biomarkers.”</p> <p>The study compared 793 participants with moderate to severe osteoarthritis of the knee who did not use NSAIDs, with 277 patients who received sustained treatment with NSAIDs for more than a year. Each patient underwent Magnetic Resonance Imaging (MRI) scans of the joint, which were then repeated after four years.</p> <p>The researchers were able to assess the images for indications of inflammation and arthritis progression including cartilage thickness and composition.</p> <p>The data showed the group using NSAIDs, had worse joint inflammation and cartilage quality than those not using NSAIDs, at the time of the initial MRI scan. And the follow-up imaging showed the conditions had worsened for the NSAID group.</p> <p>“In this large group of participants, we were able to show that there were no protective mechanisms from NSAIDs in reducing inflammation or slowing down progression of osteoarthritis of the knee joint,” said Luitjens.</p> <p>According to Luitjens, the common practice of prescribing NSAIDs for osteoarthritis should be revisited as there doesn’t appear to be any evidence they have a positive impact on joint inflammation nor do they slow or prevent synovitis or degenerative changes in the joint.</p> <p>There is also a possibility that NSAIDs simply mask the pain. Despite adjusting the study’s model for individual levels of patient physical activity, “patients who have synovitis and are taking pain-relieving medications may be physically more active due to pain relief, which could potentially lead to worsening of synovitis,” said Luitjens.</p> <p>Luitjens hopes future studies will better characterise NSAIDs and their impact on osteoarthritic inflammation. With one in three people over the age of 75 in Australia suffering from osteoarthritis and an estimated one in 10 women and one in 16 men set to develop it in the future, unlocking treatment options for this crippling condition is an imperative.</p> <p><strong>This article originally appeared on <a href="https://cosmosmagazine.com/science/osteoarthritis-puzzled-antiinflammatory/" target="_blank" rel="noopener">cosmosmagazine.com</a> and was written by Clare Kenyon.</strong></p> <p><em>Image: Shutterstock</em></p>

Body